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Mesothelioma is a highly aggressive form of cancer that is characterized by a long latency period and low survival rate. Deadly asbestos particles that cause mesothelioma can stay embedded in the body for 20-50 years before the cancer is diagnosed, often leaving doctors with limited options for treatment in its advanced stages. Mesothelioma's extended latency period also results in most patients being diagnosed later in life, usually above age 50. By then they may be suffering from other health issues that compromise their immunity and make it difficult to endure more aggressive mesothelioma treatments. The situation is gradually changing with advanced inter-disciplinary mesothelioma treatment methods and promising clinical trial discoveries that may improve the prognosis of mesothelioma patients. Some of the treatment options are listed below.
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Chemotherapy is one of the most common mesothelioma treatment methods. It involves the administration of drugs to kill cancerous cells. In mesothelioma patients, these drugs are intravenously administered and often doctors will combine a couple of drugs for maximum effectiveness. One of them will serve as a primary cytotoxin and the other will act as an alkalizing factor for stabilizing healthy cells surrounding the cancerous cells.
Surgery is often performed on mesothelioma patients in an effort to remove the tumor or stopping the cancer from spreading. Pleurectomy is often recommended as a palliative treatment method in conjunction with other treatment options. The surgery involves removal of the pleural lining around the lungs and is aimed at controlling the fluid build-up to offer the patient relief from uncomfortable symptoms. In a more radical form of surgery, the entire affected lung can surgically extracted.
Radiation therapy is associated with lesser side effects and is generally considered more bearable than other treatment methods. Radiation therapy involves targeting the affected areas with light rays either through an external machine or by placing the radioactive material inside the affected region. Radiation is also used in combination with surgery to remove the leftover cancerous tissues.
Gene therapy involves combating the cancer by adjusting the expression of a mesothelioma patient's genes with a therapeutic intent. It consists of treating the cancer at a DNA level by compensating for faulty genes. "Replacement Gene Therapy" (mutated/absent genes are substituted with a normal copy of the gene) and "Knockout Gene Therapy" (suppresses the growth of tumor inducing oncogenes with the intention of making them inactive and reducing the cell growth) are two types of gene therapies.
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